Il trattamento dei sintomi della prima dentizione: un gel con effetto barriera come alternativa all’uso di farmaci analgesici

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di Serban Rosu1 , Alessandro Nanussi2, Dumitru-Emanuel Dogaru3, Roxana Oancea4

1Department of Oral and Maxillo-Facial Surgery, University of Medicine and Pharmacy, “Victor Babes” Timisoara (Romania)

2Università degli Studi di Milano – Bicocca, Milano (Italy)

3Opera CRO, Timisoara (Romania)

4Department of Preventive and Community Dentistry, and Oral Health, University of Medicine and Pharmacy, “Victor Babes” Timisoara (Romania)

 

Il Pediatra 2018; 2, 60-64

Bibliografia

  1. McIntyre GT, McIntyre GM. Teething troubles? Br Dent J 2002;192:251-255.
  2. Macknin ML, Piedmonte M, Jacobs J, Skibinski C. Symptoms associated with infant teething: a prospective study. Pediatrics 2000;105:747-752.
  3. Massignan C, Cardoso M, Porporatti AL, Aydinoz S, Canto Gde L, Mezzomo LA, Bolan M. Signs and Symptoms of Primary Tooth Eruption: A Meta-analysis. Pediatrics 2016;137(3):e20153501.
  4. Curtis LA, Dolan TS, Seibert HE. Are one or two dangerous? Lidocaine and topical anesthetic exposures in infants. J Emerg Med 2009;37:32-39.
  5. Farronato G, Tremolati M, Ceschel G, Falciola L. Hyaluronic Acid in the management of gingivitis in young patients. International Tissue Care Symposium. Abst, September 3, 2002, Frankfurt am Mein.
  6. Igić M, Mihailović D, Kesić L, Apostolović M, Kostadinović L, Janjić OT, Milašin J. Efficacy of hyaluronic acid in the treatment of chronic gingivitis in children. Vojnosanitetski Pregled 2011;68:1021-1025.
  7. Rosu S, Montanaro F. A single site, open non controlled study of efficacy and tolerability of two formulations of the medical device Gengigel Baby gel (0.2% Hyaluronic Acid) in the topical treatment of teething in infants. Medicine in Evolution 2012;17:409-15.
  8. Rosu S, Montanaro F, Rosu A, Oancea R. A randomized, open-label, parallel-group multicentre study on the efficacy and tolerability of a non-medicated, patented gel for the relief of teething symptoms in infants. Italian Journal of Dental Medicine 2017;2:45-54.
  9. Laurent TC, Fraser JR. Hyaluronan. FASEB J. 1992;6(7):2397-404.
  10. Fraser JR, Laurent TC, Laurent UB. Hyaluronan: its nature, distribution, functions and turnover. J Intern Med. 1997;242:27-33.
  11. Kavasi RM, Berdiaki A, Spyridaki I, Corsini E, Tsatsakis A, Tzanakakis G, Nikitovic D. HA metabolism in skin homeostasis and inflammatory disease. Food Chem Toxicol. 2017;101:128-138.
  12. Meyer, K. and Palmer, J.W. (1934) The polysaccharide of the vitreous humor. Journal of Biological Chemistry 1934;107:629-634.
  13. Scott JE, Secondary and Tertiary Structures of Hyaluronan in Aqueous Solution. Some Biological Consequences. Glycoforum. 1998.
  14. Chen WY, Abatangelo G. Functions of hyaluronan in wound repair. Wound Repair Regen. 1999;7:79-89.
  15. Jentsch H, Pomowski R, Kundt G, Göcke R. Treatment of gingivitis with hyaluronan. J Clin Periodontol. 2003;30:159-64.
  16. Pistorius A, Martin M, Willershausen B, Rockmann P. The clinical application of hyaluronic acid in gingivitis therapy. Quintessence Int 2005;36:531-8.
  17. Koray M, Ofluoglu D, Senemtasi A, İşsever H, Yaltirik M. The Efficacy of Hyaluronic Acid Gel in Pain Control of Recurrent Aphthous Stomatitis. Int J Dentistry Oral Sci. 2016; 3:273-275.
  18. Nolan A, Baillie C, Badminton J, Rudralingham M, Seymour RA. The efficacy of topical hyaluronic acid in the management of recurrent aphthous ulceration. J Oral Pathol Med. 2006;35:461-5.
  19. Lee, JH; Jung, JY; Bang, D. The efficacy of topical 0.2% hyaluronic acid gel on recurrent oral ulcers: comparison between recurrent aphthous ulcers and the oral ulcers of Behçet’s disease. J Eur Acad Dermatol Venereol. 2008;22:590-5.
  20. Nolan, A; Badminton, J; Maguire, J; Seymour, RA. The efficacy of topical hyaluronic acid in the management of oral lichen planus. J Oral Pathol Med. 2009;38:299-303.
  21. Sapna N, Vandana KL. Evaluation of hyaluronan gel (Gengigel(®) ) as a topical applicant in the treatment of gingivitis. J Investig Clin Dent. 2011;2:162-70.
  22. Nemezio M, Mh De Oliveira K, C Romualdo P, M Queiroz A, Wg Paula-E-Silva F, Ab Silva R, C Küchler E. Association between Fever and Primary Tooth Eruption: A Systematic Review and Meta-analysis. Int J Clin Pediatr Dent. 2017 Jul-Sep;10(3):293-298.
  23. Arana A, Morton NS, Hansen TG. Treatment with paracetamol in infants. Acta Anaesthesiol Scand. 2001;45:20-9.
  24. McIntyre GT, McIntyre GM. Teething troubles? Br Dent J. 2002;192:251-5.
  25. Tsang AKL. Teething, Teething pain and Teething remedies. International Dentistry SA 2010;12:48-61.
  26. Owais AI, Zawaideh F, Bataineh O. Challenging parents’ myths regarding their children’s teething. Int J Dent Hyg. 2010 Feb;8(1):28-34.
  27. Olczak-Kowalczyk, Turska-Szyba; Gozdowski et al. Longitudinal study of symptoms associated with Teething: Prevalence and mothers’ practices. Pediatria Polska. 2016;91:533-540.

 

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