L’anemia da carenza di ferro, come riconoscerla e trattarla

0
215

di Roberto Miniero1, Valentina Talarico2, Paola SaraccoLaura Giancotti4 Maria Concetta Galati5 Giuseppe Raiola

1Dipartimento Materno Infantile-Azienda Pugliese-Ciaccio, Catanzaro

  2 SOC di Pediatria, Azienda Ospedaliera Pugliese-Ciaccio, Catanzaro

3SOC di Ematologia Pediatrica, Città della salute e della Scienza, Torino

4 SOC Pediatria Universitaria UMG, Azienda Pugliese-Ciaccio, Catanzaro

5SOC di Oncoematologia Pediatrica, Azienda Ospedaliera Pugliese-Ciaccio, Catanzaro

Il Pediatra 2018; 2: 48-55.

Bibliografia

 

  1. Lanzkowsky P. Iron deficiency anemia. In Manual of Pediatric Hematology and Oncology. Lanzkowsky (Ed).  Elsevier  USA.  2011; 38-57.
  2. Anrews NC, Ullrich CK, Fleming MD. Disorders of iron metabolism and sideroblastic anemia. In Nathan and Oski’ Hematology of infancy and childhood Orkin SH, Nathan DG, Ginsburg D, Look AT, Fisher DE, Lux SE, (Eds) Sauders Elsevier Canada. 2009; 521-570.
  3. Lerner NB, Sills R. Iron deficiency anemia. In Nelson text of Pediatrics. 20th Edition. Kliegman RM, Stanton BF, Schor NF, St. Geme III, Behrman RE, (Eds) Elsevier Sauders. USA 2016;2323-2325.
  4. Krishnamurti L. Iron deficiency anemia. In Textbook of Pediatric Care. McInerny TK, Adam HM, Campbell DE, Kamat DM, Kelleher KJ, Hoekelman RA, ExOfficio (Eds) American Association of Pediatrics. USA. 2009; 2201-2209.
  5. van der Merwe LF, Eussen SR. Iron status of young children in Europe. Am J Clin Nutr.2017;106 (Suppl 6):1663S-1671S.
  6. Dupont C.Prévalence de la carence en fer. Archives de Pédiatrie 2017;24:5S45-5S481.
  7. Vullo C. La carenza di ferro. Medico e Bambino.1998;5, 293-298
  8. Iolascon A, Gambale A, Tortora C, Bruno M, De Falco L.La nuova diagnostica delle anemie microcitiche. Medico e Bambino. 2013;32:563-569
  9. Camaschella C. Iron-Deficiency Anemia. N Engl J Med.2015;372:1832-43.
  10. Pantopoulos K, Porwal SK, Tartakoff AM, Devireddy L. Mammalian mechanisms of iron homeostasis biochemistry 2012;51:5705-C
  11. Beoumont C, Karim K. Actualité du metabolism du fer. Med.Interne.2013; 4: 17-25.
  12. Lönnerdal B. Development of iron homeostasis in infants and young children. Am J Clin Nutr.2017;106 (Suppl 6):1575S-1580S.
  13. McCarthy EK, Chaiomh N, Kenny LC, Hourihane JO, Irvine AD, Murray DM, Kiely ME. Iron status, body size, and growth in the first 2 years of life. Child. Nutr. 2018;14. Epub 2017.
  14. Tounian P, Chouraqui JP. Iron in nutritionArchives de Pédiatrie 2017;24:5S23-5S31.
  15. Cerami C. Iron nutriture of the fetus, neonate, infant and child. Nutr. Metab. 2017;71 (Suppl.3):8-14.
  16. Gambale A, Falco L, Russo R, Andolfo I, Iolascon A. Il metabolismo del ferro: i nuovi tasselli di un grande puzzle. Prospettive in Pediatria 2017; 47:85-96.
  17. Società Italiana di Nutrizione Umana. Livelli di Assunzione di Riferimento di Nutrienti ed Energia per la Popolazione Italiana; Società Italiana di Nutrizione Umana: Milano, Italy, 2012.
  18. Peirano PD, Algarin CR, Chamorro RA, Reyes SC, Duran SA, Garrido MI, Lazoff B. Sleep alterations and iron deficiency anemia in infancy.  Sleep Medicine 2010; 11:637-642.
  19. Beard J. Recent evidence from human and animal studies regarding iron status and infant development. J.Nutr.2007;137:524S-530S.
  20. Vendt NC, Kool P, Teesalu K, Lillemäe K, Maaroos HI, Oona M. Iron deficiency and Helicobacter pylori infection in children. Acta Pediatrica 2011;100:1239-43.
  21. Mahoney DH. Iron deficiency in infants and young children: screening, prevention, clinical manifestations and diagnosis. Uptodate 2012.
  22. Johnson-Wimbley TD, Graham DY. Diagnosis and management of iron deficiency anemia in the 21st Ther Adv Gastroenterol. 2011; 4:177-184.
  23. Baker RD, Greer FR. Diagnosis and prevention of iron deficiency and iron –deficiency anemia in infants and young children (0-3 years of age). Pediatrics.2010;126: 1040-1050.
  24. Urrechaga T, Borque L, Escanero JF. The role of automated measurement of red cell subpopulations on the sysmex XE 500 analyzer in the differential diagnosis of microcytic anemia Int. Jnl lab. Hem. 2011; 33:30-36.
  25. Mast AE, Blinder MA, Dietzen DJ. Reticulocytes haemoglobin content. Am. J. Hematol. 2008; 83:307-310.
  26. Ullrich C, Wu A, Armsby C, Rieber S, Wingerter S, Brugnara C, Shapiro D, Bernstein H. Screening healthy infants for iron deficiency using reticulocyte haemoglobin content Jama 2005;294:24-31.
  27. Parodi E, Giraudo MT, Davitto M, Ansaldi G, Mondino A, Garbarini L, Franzil A, Mazzone R, Russo G, Ramenghi U. Reticulocyte parameters: markers of early response to oral treatment in children with severe iron deficiency anemia. J Pediatr Hematol Oncol. 2012 34):e249-52.
  28. Urrechaga T. Red blood cell microcytosis and hypocromia in the differential diagnosis of iron deficiency and B-thalassemic trait. Jnl lab. Hem. 2009;31:528-534.
  29. Soldin OP, Bierbower LH, Choi JJ, Thompson-Hoffman S, Soldin SJ. Serum iron, ferritin, transferrin, total iron binding capacity, hs-CRP, cholesterol and magnesium in children. New reference intervals using DADE dimension clinical Chemistry system. Clinical Chimica Acta 2004;342:211-217.
  30. Beard JL, Murray-Kolb LE, Rosales FJ, Solomons NW, Angelilli ML. Interpretation of serum ferritin concentrations as indicators of total –body iron stores in survey population: the role of biomarkers for the acute phase response. Am. J. Clin. Nutr 2006,84.1498-1505.
  31. Thuret A. Diagnostic biologique de la carence martiale chez l’enfant. Archives de Pédiatrie 2017;24:5S6-5S13.
  32. Thurnham DI, Mc Cabe LD, Haldar S, Wieringa FT, Northrop-Clewes CA. Adjusting plasma ferritin concentrations to remove the effects of subclinical inflammation in the assessment of iron deficiency: a meta-analysis. Am. J. Clin. Nutr 2010;92:546-555.
  33. Daru J, Colman K, Stanworth SJ, De La Salle B, Wood EM, Pasricha Serum ferritin as an indicator of iron status: what do we need to know? Am J Clin Nutr.2017 Dec;106 (Suppl 6):1634S-1639S.
  34. Speeckaert MM, Speeckaert R, Delanghe JR. Biological and clinical aspects of soluble transferrin receptor. Critical Reviews in Clinical laboratory Science 2011; 47:213-228.
  35.  Celi J, Samii K, Perrier A, Reny JL. Anémie ferriprive, inflammatoire ou mixte: comment orienter le diagnostic? Rev Med Suisse 2011;7: 2018-23.
  36. Bosco C, Favrat B, Cheseaux M. Carences en vitamine B12 et fer: du diagnostic au suivi. Rev Med Suisse. 2012;8: 1348-51.
  37. Huang S, Yang Y, Cheng C, Chen J, Lin C. The etiology and treatment outcome of iron deficiency and iron deficiency anemia in children. J. Pediatr. Hematol. Oncol. 2010; 32:282-285.
  38. Clénin GE. The treatment of iron deficiency without anemia in otherwise healthy persons. Swiss Med Wkly. 2017; 147:w14434.
  39. Martius C. Carence martiale sans anémie – un sujet brûlant? Conséquences non

hématologiques de la carence martiale:lesquelles sont confirmées, quand sont-elles importantes? Forum Med Suisse 2009; 9:294–299.

40. Muñoza M, Gómez-Ramírezb S, Bhandaric S. The safety of available treatment options for iron-deficiency anemia. Expert opinion on drug safety. 2018.

41. McDonagh M, Blazina I, Dana T, Cantor A, Bougatsos C. Routine Iron Supplementation and Screening for Iron Deficiency Anemia in Children Ages 6 to 24 Months: A Systematic Review to Update the U.S. Preventive Services Task Force Recommendation. Agency for Healthcare Research and Quality (US); 2015 Mar. Report No.: 13-05187-EF-1.

42. McDonagh MS, Blazina I, Dana T, Cantor A, Bougatsos C. Screening and routine supplementation for iron deficiency anemia: a systematic review. Pediatrics.2015 Apr;135(4):723-33

43. VL Miniello, MC. Verga, L. Diaferio, P. Falco, P. Giordano. Chi supplementare con ferro? Pediatria Preventiva&sociale.2017; Anno XIII:9-23.

44. AA.VV. Consensus SIPPS – FIMP – SIMA. VIS. Vitamine-Integratori.2017. Supplemento, Pagg. 196-358.

45. Zuccotti GV, Cassatella C, Morelli A, Cucugliato MC, Catinello G, del Balzo V,

Guidarelli L, Agostoni C, Mameli C, Troiano E, Bedogni G. Nutrient intake in italian infants

and toddlers from north and south italy: The Nutrintake 636 Study Nutrients 2014, 6: 3169-

3186.

  1. Penagini F, Abbattista L, Borsani B, Ramponi G, D’Auria E, Zuccotti GV. Iron

deficiency and iron deficiency anemia in children aged 6-36 months: Is there room for

improvement of screening, prophylaxis and treatment? Pharmacol Res. 2017 Dec 16. pii:

S1043-6618(17)31470-6. [Epub ahead of print]

 

 

 

 

 

LASCIA UN COMMENTO

Please enter your comment!
Please enter your name here